Luke is Alive - April 07
Stress affects hair growth.
A study in mice confirms that stress hormones suppress hair growth through regulation of hair follicle stem cells.
When corticosterone levels are high, the hair follicles remain in a prolonged resting phase and do not regenerate. But if this hormone is reduced, the stem cells of the hair follicle are activated and the growth of new hair occurs.
Now, the team led by Ya-Chieh Hsu shows how in mice corticosterone (a hormone released during times of stress, equivalent to cortisol in humans) regulates the activity of hair follicles. The results are published this week in the journal Nature.
"Chronic stress, through corticosterone upregulation, inhibits an activation signal in cells surrounding hair follicle stem cells, which normally promote hair growth," says Hsu. "Although stress can be detrimental to different skin stem cells, the mechanisms by which changes are triggered in tissues can be diverse, and much remains to be learned."
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